Two Roman and one Greek city were famous for their destruction by volcanoes although others were destroyed.
Pompeii. Nestled on the Northern slopes of Vesuvius, the city was destroyed at least three times as historians record it.
Herculaneum. This coastal city was destroyed twice that we know of, once when the city was in its infancy and the second after it had become the port of call for most of the Mediterranean.
Callifea. A little south of Herculaneum, this city was destroyed twice by Vesuvius during the Etruscan period. The first destruction in 138 BCE flattened the city in an earthquake and the second destruction four years later via pyroplastic flow made Callifea a moonscape. Pliny the Elder records the events virtually as a sidenote.
Other people asked questions on similar topics, check out the answers they received:
Other people asked questions on various topics, and are still waiting for answer. Would be great if you can take a sec and answer them