What do you think is the greatest invention that benefitted humanity: other than sliced bread and frozen pizza (that's a joke, folks) ?

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The printing press.

Don't sweat the petty things and don't pet the sweaty things.

That's a good one.

And how about zippers? They were undoubtedly a boon to hygeine - no more peeing in the streets out of desperate need; if a chamber pot or water closet was nearby, you could go do your business in private - and in a hurry! 

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Refrigeration.  It has not only brought comfort to millions, but it's medical applications have saved lives.  Also, the benefits of food preservation.

I'd agree with you, but then we'd both be wrong.

cooking fires

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The invention of radial tires has increased safety and wear while decreaing cost over bias ply/recapped tires to such an extent it has to be one of the top inventions in the later quarter of the 20th century. 

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Wonderful replies!! Let's expand the question to include discoveries!

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