Clindoxyl gel is very good for removing acne but it can cause itching, dryness or redness. A client says it removes acne overnight but it leaves the skin dry. For that I used a moisturizer, after that I used it and it removed my acne and have no other issue. This is minor side effect and clindoxyl gel usually has no major side effect. But in very rare cases, its side effect can be stomach cramping or pain, throwing up, or extremely watery diarrhea. If the user feels problems in breathing, swelling hives or rashes he should immediately leave the use of clindoxyl gel and contact physician. This is made for adults and children above the age of twelve, not applicable for children below twelve years.